Amendment 2, the amendment for medical marijuana, failed to pass in Florida by 2.54 percent.
The amendment would have provided medical marijuana to those who are determined by a licensed Florida physician to have a debilitating diseases. The amendment needed 60 percent of the "yes" Florida votes to pass and only received 57.46 percent.
In Orange County, the amendment received 58.9 percent of the vote.
Although the Charlotte's Web medical marijuana bill has already been signed into law in the state, supporters say Amendment 2 would have allowed for a more accessible distribution of the substance to those qualified.
The Associated Press reports that the campaign for medical marijuana has been the most expensive ballot initiative across the nation.